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    Maria Gabriella MATERA

    Insegnamento di PHARMACOLOGY 1

    Corso di laurea magistrale a ciclo unico in MEDICINA E CHIRURGIA

    SSD: BIO/14

    CFU: 5,00

    ORE PER UNITÀ DIDATTICA: 50,00

    Periodo di Erogazione: Annualità Singola

    Italiano

    Lingua di insegnamento

    INGLESE

    English

    Teaching language

    English

    Contents

    Knowledge of general principles of pharmacodynamic, pharmacokinetic and drug interaction; knowledge of drugs acting at neurotransmissions. Knowledge of toxicology included drug abuse and treatment of poisoning

    Textbook and course materials

    Book: Rang &Dale’s 11th edition
    Goodmann and Gilmans: The pharmacological basis of therapeutics 13 Edition

    Course objectives

    Correlation of pharmacology with related medical sciences emphasizing the application of pharmacodynamics and pharmacokinetics to therapeutics

    Prerequisites

    knowledge of biochemistry, physiology, physiopathology

    Teaching methods

    classroom
    Frontal lessons. Students are also provided with educational material both in paper form and in ppt or pdf presentation. This material does not replace in any way one or more textbooks

    Evaluation methods

    Evaluation of student proficiency is based on oral test (viva voce). The oral exam covers all the aspects of the theory of pharmacology. The questions will be as specific to evaluate the basic knowledge of the topic. The student should be able to discuss on the topic and be able to connect and analyze the different subjects. This means that the student must know the key steps of basic pharmacology, the most relevant for the therapy. Moreover, the student must have a deep knowledge of the most common therapies being able to connect the drugs with diseases. In order to test the acquisition of this ability the student will be asked to solve simple clinical therapeutic oriented problem, e.g recognize a possible drug interaction, the possible adverse reactions and their clinical manifestation. The final grade is expressed in 30/30 were 18 represents the minimum and 30 the maximum and it is established during the oral exam. Oral exam lasting 30 minutes.

    Course Syllabus

    Pharmacodynamic: general principles, molecular aspect, cellular aspect -Pharmacokinetics: absorption, distribution, metabolism and excretion -Pharmcokinetic parameters -Drug interactions -Chemical mediators and autonomic nervous system: Cholinergic, Noradrenergic, GABAergic, glutammatergic, Opioid, Cannabinoid, 5-HT and histamine system- Purines, peptides and nitric oxide -Principles of toxicology included drug abuse and treatment of poisoning

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